Standardized high reproducibility hIPSC differentiation processes leading to identical physiological properties
5D-brains mature 4 times faster than organoids current 3D models, and deliver reliable preclinical data in less than 3 weeks
5D-brain is the sole 3D model capable of monitoring individual neurons’ activity over the whole network throughout all its developmental stages
Proprietary processes to obtain in vivo like human neuronal networks in vitro
5D-brains are in vitro models tailor made to address physiological and pharmacological questions
Global comprehensive analysis of the nervous system response to predict: target, dose effects, efficacy and regulation pathways
Synaxys realizes preclinical assays and R&D projects to rapidly predict the response of the human nervous system before starting clinical trials.
Our platform offers a wide range of electrophysiological assays with supporting microscopy, genomic and proteomic data for a comprehensive analysis. Using our proprietary 5D-brain models, we propose custom pharmacology and toxicology screens on neural functions to identify the targets and actions of a compound.
Synaxys 5D-brain models are long lived and composed of all the neuronal cell types with their regulating elements. These intrinsic properties enable them to bring pertinent data on:
Synaxys offers three complementary levels of services
Synaxys operates as a contract research organization
Sophie Pautot (PhD Applied Physics from Harvard, HDR) has a multi-disciplinary training and more than 15 years of experience leading high impact cross-disciplinary projects in neuroscience. She pioneered the processes that serves as scientific foundation to Synaxys 5D-brains.
Michel Fareng (graduated from HEC) is a serial entrepreneur. For decades, he was involved in sport management, culture and education. Today he focuses on sustainable activities, environment and health issues.
Photos : Lionel Pesqué